Phd Studentship, Analytics, Environmental & Forensics

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description Revolutionising Infection Diagnosis Through Targeted Radiometal Imaging . Background of the Project: . People with conditions like heart disease, diabetes, cancer, organ transplants, or immunodeficiencies face higher risks of infection, complications, and death. Prompt and accurate diagnosis is vital to improve outcomes in these vulnerable groups. However, clinical diagnosis of microbial infections is often challenging, and noninvasive methods tend to perform poorly. Existing lab techniques typically require invasive sample collection, followed by time-consuming culture and antibiotic resistance testing. These methods delay results and lack real-time monitoring to assess disease burden or pinpoint the infection site. Imaging tools that specifically target pathogens are highly sought after to improve noninvasive infection diagnosis and localisation. Currently, no clinical imaging test can reliably distinguish infections from inflammation or malignancy or differentiate between bacterial and fungal infections. Emerging research is exploring radiometals conjugated with targeting molecules for in vivo imaging of infections via PET or SPECT. These agents can also be linked to therapeutics, enabling combined diagnosis and targeted antimicrobial treatment (theranostics)—offering a promising tool in the fight against antimicrobial resistance (AMR). At King’s College London, in collaboration