EURAXESS
Postdoctoral fellow in epithelial metabolism and kidney fibrosis
INSERM
Sponsorship not confirmed
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About the job
id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description Welcome to our Team in Paris! The successful candidate will join the Kidney, Vessels, Inflammation and Metabolism (KVIM) team, which studies how immune, vascular and metabolic pathways shape kidney injury and fibrosis. We investigate the cellular and molecular mechanisms that drive human kidney diseases, from early injury to organ failure. Kidney failure is expected to rank among the top five causes of death in the next 15 years, and chronic kidney disease is a major contributor to cardiovascular mortality and cognitive ageing, making this research area highly impactful. The postdoctoral project will focus on understanding how epithelial metabolic programs shape signalling with fibroblasts and immune cells in the fibrotic kidney niche, using both experimental models and human samples. Main tasks and responsibilities. • Lead an independent research project on epithelial metabolism and kidney fibrosis. • Use a broad translational toolbox, including cell culture and organoids, mouse genetics, and deeply phenotyped human samples and datasets. • Integrate experimental work with advanced analysis of clinical and multi‑omics data to identify disease mechanisms, biomarkers and therapeutic targets. • Present results in lab meetings, conferences, and contribute to manuscript preparation. Profile and requirements. • PhD (or equivalent) in biomedical sciences (e.g. cell biology, physiology, nep
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