Postdoctoral position in bacterial genomics

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description A Genomic Time Machine: Reconstructing the Lost Diversity of Salmonella Typhi . Location: Institut Pasteur, Paris, France. Duration: 2-3 years. Principal Investigator: François-Xavier Weill. We are seeking an outstanding postdoctoral researcher with a strong background in bacterial genomics and evolutionary biology to join an ambitious project that will reconstruct the twentieth-century global evolution of Salmonella enterica serotype Typhi ( S. Typhi), the human-restricted pathogen causing typhoid fever. This project offers a rare opportunity to work on a unique historical genomic resource and to answer fundamental questions in pathogen evolution by reconnecting classical epidemiology with modern bacterial genomics. The project . Before the genomic era, the worldwide surveillance of typhoid fever relied on Vi phage typing, which served for decades as the international standard for strain discrimination. Beginning in 1947, laboratories around the world published regular inventories documenting the geographical and temporal distribution of S. Typhi phage types. Together, these reports constitute an extraordinary historical record of the global circulation of this pathogen. However, because phage typing has now disappeared from routine practice, this remarkable epidemiological resource has become largely inaccessible to contemporary microbiology. Our goal is to bring it back to life.