EURAXESS
Postdoctoral Researcher (18 months) - SPARTA
Aix Marseille Université
Sponsorship not confirmed
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About the job
id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description SPARTA – Single-cell Phenotyping And Radiobiological Tritium Assessment . 1. General information . Workplace: IMBE, Mediterranean Institute of Marine and Continental Biodiversity and Ecology (UMR AMU-CNRS-IRD-Avignon Université), SANTES Team, Timone Campus, Marseille, France. Contract duration: 18 months. Expected start: December 2026. Employment: Full-time (35 h/week). Salary: According to Aix-Marseille University postdoctoral salary scale. Required degree: PhD in Biological Sciences. Desired experience: Environmental genetic toxicology, imaging flow cytometry, radiotoxicology. 2. Mission . The SPARTA project aims to establish a new paradigm for assessing the biological risk associated with micrometric stainless steel particles representative of those generated during maintenance and decommissioning of present and future facilities using tritium (the radioactive hydrogen isotope), such as fusion power plants. The experimental study will be performed using hydrogenated particles to mimic tritiated ones. Building on the European TRANSAT and TITANS projects, SPARTA shifts from conventional population-based toxicology towards quantitative single-cell radiobiology. Differentiated THP-1 macrophages will be analysed using the AMUTICYT imaging flow cytometry platform. For each individual cell, particle burden, particle geometry, particle-to-nucleus distance, reactive oxygen species (ROS),
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