PhD Thesis (M/F) Human neural stem cell lineages

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description The hosting structure . The Curie Institute Research Center . Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities. Context . Laboratory . The Baffet lab is located at Institut Curie, in the department of cell biology (UMR144). http://institut-curie.org/team/baffet . The team investigates the mechanisms of mammalian neocortex development, with a strong focus on neural stem cells. We aim to understand how these cells shape the cel type diversity of the brain, using live imaging-based approaches. Description of the PhD thesis project . The remarkable expansion of the human neocortex during recent primate evolution is thought to result from increased production of neuronal and glial cells by neural stem cells, known as radial glial (RG) cells. However, the cell fate decisions that generate this diversity, and how they vary across developmental stages and cortical regions, remain poorly understood. This PhD project aims to uncover the lineage relationships and fate decisions of human neural stem cells across cortical regions using a combination of human fetal tissue