EURAXESS
Postdoctoral Position – Cancer Immunology & Immunometabolism
iGRED
Sponsorship not confirmed
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About the job
id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description Projet : Microenvironment Metabolism-Adapted Vaccination for Enhanced Reactivation of Immunosurveillance in Advanced Prostate Cancer. The NuReP team (Nuclear Receptors & Pathophysiology) at iGReD – Université Clermont Auvergne/CNRS/Inserm is seeking a highly motivated postdoctoral researcher to join the INCa-funded MAVERIC project. The successful candidate will play a central role in the project and will:. - Develop and characterize genetically engineered and orthotopic prostate cancer models (CRISPR, lineage tracing,. surgery). - Investigate dendritic-cell and antitumor immune responses following LXR modulation and vaccination. - Perform spectral cytometry, cell sorting, scRNA-seq and spatial transcriptomics, including downstream data analysis. - Conduct cellular and molecular experiments using tumor and immune-cell models. - Collaborate with chemists developing novel LXR ligands and with the multidisciplinary MAVERIC consortium. - Contribute to publications, international conferences and dissemination of project findings. Where to apply E-mail [email protected]. Requirements Research Field Biological sciences » Biology Education Level PhD or equivalent . Skills/Qualifications. iGRED is looking for a PhD scientist in immunology, cancer biology or a related field, with:. - A strong background in cancer immunology / tumor microenvironment; expertise in dendritic cells is a strong
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