Study Engineer (F/M)

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description The host institution . The Institut Curie Research Center . France’s leading cancer research and treatment center, Institut Curie unites a renowned research center and a specialist hospital, fostering close collaboration between scientists, clinicians and healthcare professionals. It offers an environment of excellence where expertise comes together around shared values: care, humanity, openness, collaboration, efficiency, innovation, solidarity and commitment. Job description . Team “Mechanisms of Repression by Polycomb Group Proteins” . Our research team aims to understand the principles that govern gene regulation by the highly conserved family of chromatin modifiers known as Polycomb proteins, from the biochemical to the cellular and organismal levels. We are affiliated with the Institut Curie Research Center’s Genetics and Developmental Biology Unit (Inserm U934/CNRS UMR3215). https://institut-curie.org/team/margueron. Missions . Perform CRISPR-based genetic screens coupled to single cell transcriptomics. Engineer various stem cell models (iPS, ES) by genome editing and characterize their transcriptomic and epigenomic properties. Conduct biochemical studies of novel Polycomb-associated proteins. Participate in all common tasks such as equipment maintenance, renewing stocks, student training, etc. Activities . Cloning . Library preparation (RNA-seq, CUT&RUN-seq, etc.) . Protein