Postdoctoral researcher (M/F) in bioorganic chemistry / chemical biology

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description The postdoctoral researcher will be involved in a multidisciplinary research project aimed at developing the synthesis of polyazamacrocyclic compounds as ligands for non-canonical nucleic acid structures (including DNA three-way junctions) with anticancer applications, and at functionalizing them for applications in chemical biology. - Organic synthesis and molecular characterization. - Participation in chemical biology experiments (in collaboration with a partner team). The proposed position is part of a multidisciplinary project funded by AVIESAN and dedicated to the development, optimization, and functionalization of ligands targeting DNA three-way junctions for cancer treatment, as well as the development of chemical tools to study their mechanisms of action in cellulo. This project is conducted in collaboration with teams from the Institut de Pharmacologie et de Biologie Structurale (Toulouse) and Université Bourgogne Europe (Dijon). The host team, "New Synthetic Methods for the Chemistry-Biology Interface," is part of the CNRS UMR8601 unit "Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques," located at Université Paris Cité (Paris 6th arrondissement). The team's research spans a broad range of topics in synthetic organic chemistry and chemical biology, all grounded in molecular innovation. Our work involves exploring new chemical spaces, as well as developi