Postdoctoral Researcher (M/F) in Cellular Biophysics

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description The postdoctoral researcher will participate in the DEVIN project (Numerical Modeling of DNA Electroporation Vaccination), which aims to investigate the physical mechanisms underlying the electropermeabilization of biological membranes and DNA transfer using pulsed electric fields. They will conduct experimental work on membrane and cellular models, in connection with the numerical modeling approaches developed within the project, and contribute to the dissemination and promotion of the scientific results. - Preparation and characterization of giant unilamellar vesicles (GUVs). - Conducting electroporation experiments using pulsed electric fields on lipid membranes and cultured cells. - Investigating membrane permeabilization, morphological changes, and lipid peroxidation. - Culturing adherent cells and conducting plasmid DNA transfer experiments. - Optical and fluorescence microscopy, image acquisition, and quantitative image analysis. - Processing and analyzing experimental data and comparing the results with numerical models. - Presenting research findings and writing scientific publications. The position is based at the IPBS (Institute of Pharmacology and Structural Biology) in Toulouse, within the Cellular Biophysics team, which specializes in the interactions between electric fields and biological systems. The DEVIN project brings together the IPBS, the Inria Centre at the Uni