Postdoctoral researcher Auto-piloting of magnetic microswimmers for in-vitro thrombolysis (M/F)

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description In a brain stroke, the formation of thrombus blocks blood flow and prevents oxygenation of certain areas of the brain. Treatment is based on rapid delivery of the thrombolytic agent (t-PA), but the delivery of the drug is limited by the obstruction of the vessels. In this project, the post-doctoral fellow will be tasked to improve the transport of a thrombolytic drug (t-PA) to the clot using self-assembling magnetic micro-swimmers. He/she will also contribute to the implementation of a system of self-piloting and guidance of these micro-swimmers as well as controlled release of the t-PA and monitoring of the dissolution of clots, in combination with a real-time optical visualization in a microfluidic network. • Study of the fidelity of the movement of micro-swimmers to the target trajectory. • Coupling of the release of the active ingredient and the dissolution of model clots (fibrin matrices from commercially available plasma). • Analysis of the results. INPHYNI's activities are based on three main axes: Waves and quantum physics; Photonics; and Nonlinear physics, complex fluids and biophysics. The projects developed around these themes cover theoretical, fundamental and experimental aspects as well as applications. These projects benefit in particular from the support of technological platforms and high-performance administrative and technical shared services. Experimental activit