Post doctoral - M/F

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description -Design and conduct, with scientific autonomy and in consultation with the team leader, research projects on the role of retrotransposons in gene regulation and changes in cellular state, incorporating transcriptomic and epigenomic data. Formulate scientific hypotheses, define analytical strategies, and interpret results within their biological context. • Analyze transcriptomic and chromatin accessibility data at the single-cell or single-nucleus level (sc/snRNA-seq, sc/snATAC-seq, multiome). • Identify retrotransposons associated with cellular programs and characterize their links to genes and regulatory networks. • Study responses to changes in the cellular environment, particularly hypoxia and immune activation, as well as differentiation and neurogenesis programs. • Contribute to the development and validation of methods for quantifying retroelements, notably RETROSCAPE, and integrate public and internal data. • Develop statistical analyses and reproducible workflows; document methods, data, and code. • Work with experimental biologists to define relevant validations and incorporate their results into the analyses. • Draft manuscripts, present results, and contribute to grant proposals related to their projects. The RETROGEN team, led by Manvendra Singh at INEM, studies the role of retrotransposons in genome regulation, development, and human diseases. It combines functional gen