EURAXESS
Research Engineer position - Expert in Biochemistry of tRNA
Institut de Biologie Structurale
Sponsorship not confirmed
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About the job
id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description . We are seeking a highly motivated research engineer to join the NMR of Large Assemblies ( NMRLA ) group. This is a unique opportunity to contribute to cutting-edge structural biology research, focusing on the synthesis, purification and optimisation of tRNA for advanced cell-free and structural biology applications. Your mission: . As part of our ERC-funded project, you will: . • Be responsible for setting up efficient large-scale in vitro and in vivo production of multiple tRNAs. • Design molecular biology and enzymology techniques to produce homogeneous, functional tRNAs. • Develop and optimise protocols to purify tRNAs on a large scale using FPLC chromatography under native conditions. • Work in a dedicated RNase-free environment to ensure the highest quality RNA production. • Be part of a dynamics collaborative teams and contribute to the development of a novel interdisciplinary method that aims to reprogram the genetic code for the site-specific incorporation of isotope-labelled amino acids for use in biomolecular NMR applications. Why this job is for you: . - High-impact research : Make a valuable contribution to groundbreaking advancements in cell-free and structural biology technologies. - Lead a tRNA synthesis project : Take responsability of a key project from design to production. - Develop your expertise : enhance your skills in the reproducibility, scalability and opt
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