PhD Candidate (f/m/x) - Regulation of Liver Metabolism by miRNAs

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description Area of research: . PHD Thesis. Job description: PhD Candidate (f/m/x) - Regulation of Liver Metabolism by miRNAs . 103052. Full time. 39 hrs./week. Neuherberg near Munich. At Helmholtz Munich, we develop groundbreaking solutions for a healthier society in a rapidly changing world. We believe that diverse perspectives drive innovation. Through strong partnerships, we accelerate the transfer of new ideas from the lab to real-life applications, improving lives. The group of. Diabetes Complications. from the Institute for Diabetes and Cancer (IDC) . (headed by Prof. Stephan Herzig) is currently seeking a highly motivated student (f/m/x) to develop a PhD project on miRNAs with a role in liver metabolism . You will continue our line of research on the miR-379/miR-410 cluster of miRNAs (please see PMID: 42768048). Our aim is to identify miRNAs involved in the development of insulin resistance and diabetes, as well as in the progression of MASLD (metabolic dysfunction-associated steatotic liver disease, commonly called fatty liver disease), that could serve as targets for novel RNA therapies. Your tasks . Investigate how miRNAs influence liver metabolism, and plan and run your own experiments. Work with primary liver cells (hepatocytes) from humans and mice, and build cell models for insulin resistance and MASLD. Analyse molecular datasets (e.g. RNA sequencing) and interpret your results.