Postdoctoral researcher (M/F) in the biochemistry and biophysics of RNA systems

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description Develop and experimentally characterise RNA networks capable of reproduction, variation and selection, and analyse the effects of compartmentalisation and physicochemical conditions on their evolutionary dynamics. - Design, produce and purify functional RNAs and the components of reaction networks. - Implement and characterise autocatalytic and self-reproducing RNA systems using biochemical and biophysical measurements and quantitative analyses. - Investigate ligation, recombination, amplification and information-transfer reactions within RNA networks. - Measure the effects of compartmentalisation, dilution, environmental cycles and other physicochemical constraints on network stability and dynamics. - Analyse the relationship between molecular composition, reproduction rate, persistence, heredity and response to selection. - Develop reproducible protocols, analyse data and document results. - Contribute to PEPR Origins meetings, scientific reports, publications and project presentations. - Take part in the team's scientific discussions, project collaborations, the unit's scientific activities, seminars and collective activities related to the project. The position is part of PEPR Origins and the Synthetic Biosystems team's research on the emergence of evolving prebiotic systems. The project focuses on RNA reaction networks combining autocatalysis, molecular reproduction and mechani