Post-doctoral fellowship in biochemistry/glycobiology – M/F

id="offer-description" class="ecl-u-type-heading-2 ecl-u-mt-none ecl-u-mb-l">Offer Description Study the structure and functional properties of a bacterial sulfatase targeting glycosaminoglycans. Generate and characterize mutants aimed at improving the enzyme's properties. - Express and purify recombinant enzymes. - Perform enzymatic activity assays and determine kinetic parameters. - Develop protein design approaches to generate mutants with improved enzymatic properties. - Validate the enzymatic properties of selected mutants. - Determine the structures of selected mutants using X-ray crystallography. - Present research findings at scientific congresses and conferences. - Write activity reports and scientific publications. Located on the Grenoble Science Park (ESRF/ILL/EMBL/IBS), the Institute of Structural Biology (IBS) is a national and international player in the field of integrated structural biology. The IBS is a research center, a technical platform, a host site and a scientific training center. Its mission is to develop research in structural biology, a field of research that is crucial to the understanding of fundamental biological mechanisms. It is supported by 12 state-of-the-art platforms. As a joint research unit (CEA-CNRS-UGA), the IBS is composed of 20 research groups, each of which proposes a multi-disciplinary approach, at the frontiers of biology, physics and chemistry, in coherence with 3 research axes. Nearly 320 people work there as researchers, PhD stud