Senior Vice President, Clinical Development

Recursion · New York, New York Recursion is seeking an accomplished clinical development leader to serve as Senior Vice President, Clinical Development. This is a senior operational and strategic role responsible for driving the clinical execution of the company's differentiated pipeline across oncology and rare disease, reporting directly to the Chief Medical Officer. The SVP will serve as the primary architect of clinical development strategy at the program level, translating scientific vision into rigorous, efficiently executed trials that generate compelling data packages to support regulatory advancement and eventual approval. Responsibilities: Lead the clinical strategy, design, and execution of oncology and rare disease programs. Define and execute clinical development strategy for assigned programs, including study design, endpoint selection, patient population strategy, and regulatory pathway. Lead the design, initiation, and oversight of early and late-stage clinical trials across oncology and rare disease indications. Partner with organization's ClinTech organization to embed clin tech within the clinical development function. Provide direct leadership and mentorship to a team of clinical development professionals. Partner closely with Regulatory Affairs to lead FDA and international agency interactions. Collaborate with Clinical Operations to ensure trials are delivered on time, on budget, and to the highest quality standards. Integrate with Translational Medicine and Biostatistics to develop biomarker strategies and adaptive trial designs. Oversee clinical safety monitoring, adverse event review, risk management, and interactions with Independent Data Monitoring Committees. Contribute to portfolio prioritization decisions and resource allocation discussions. Represent the company externally at scientific conferences, advisory boards, and key opinion leader engagements. Support business development due diligence, partnership discussions, and potential in-licensing evaluations. Contribute clinical content for investor communications. Requirements: 15+ years of clinical development experience, with substantial time spent in oncology, rare disease, immunology, or precision medicine. MD, MD/PhD with specialization in oncology, hematology, rare disease, immunology, or a related biomedical discipline. Demonstrated experience leading Phase 1 and Phase 1/2 clinical trials for novel mechanisms. Strong track record of cross-functional program leadership. Experience working in or comfort operating within a TechBio, data science-forward, or AI-enabled drug development environment. Direct experience engaging with FDA and other regulatory agencies. Proven ability to operate with scientific rigor and operational discipline in a resource-constrained, clinical-stage company. Strong scientific acumen in small molecule drug development, kinase biology, oncology mechanisms of action, or rare disease pathophysiology. Exceptional communication and leadership skills.