Production Chemist, CGMP Manufacturing

Hims & Hers · Menlo Park, California · onsite Hims & Hers is the leading health and wellness platform, on a mission to help the world feel great through the power of better health. The Production Chemist performs hands-on cGMP peptide manufacturing, supporting either upstream operations (synthesis and cleavage) or downstream operations (preparative HPLC purification and lyophilization). Responsibilities: Execute assigned manufacturing tasks per approved batch records, SOPs, and work instructions with minimal supervision, in a timely and efficient manner. Perform SPPS and cleavage operations, including resin preparation, synthesizer operation, cleavage, precipitation, and crude peptide isolation. Verify protected amino acids batch by batch against specification, including solubility and appearance, before use. Perform prep HPLC purification, fraction pooling, concentration, lyophilization, and final packaging. Check analytical HPLC and mass of dissolved crude peptide and identify the target peptide peak by integration and mass spectrometry to guide purification and fraction pooling. Handle raw materials, solvents, and reagents safely; operate and clean production equipment and instruments. Prepare and label chemical solutions and buffers according to standard formulas. Perform in-process checks and escalate unexpected results right away. Complete batch records, logbooks, and standardized forms accurately and in real time. Review data for accuracy and completeness before submission and perform data analysis as assigned. Report deviations promptly, keep the work area clean, organized, and inspection-ready, and complete GMP and safety training on time. Work closely with teammates, Quality, QC, and Maintenance, and take part in cross-training. Requirements: Bachelor’s degree in chemistry, Biochemistry, Chemical Engineering, or a related discipline. Hands-on laboratory experience, through coursework, internships, or work. Strong attention to detail and the ability to follow procedures precisely and document accurately. Strong communication and time management skills, and ability to work independently and as part of a fast-moving team. Ability to stand for extended periods, lift up to 40 lbs., and wear required PPE. Preferred Qualifications: Background or hands-on experience in peptide synthesis (SPPS), from academic research, an internship, or industry (upstream). Experience with HPLC purification or lyophilization (downstream). Familiarity with analytical HPLC and mass spectrometry for in-process data review. Prior exposure to cGMP or regulated environments. Benefits: Competitive salary & comprehensive health benefits including medical, dental & vision.